EASL clinical practice guidelines on haemochromatosis
European Association for the Study of the Liver (EASL) · 2022 · Journal of Hepatology 77(2):479-502
What this work gives Aellic
In HFE C282Y homozygotes, transferrin saturation above 45 percent with ferritin above 200 ug/l in women (above 50 percent and 300 ug/l in men and postmenopausal women) is enough to diagnose haemochromatosis; used as the upper end of the transferrin saturation band.
Correction of 25 October 2026
The registry called a transferrin saturation of 45 percent or more a screening threshold for iron overload on its own. The guideline uses above 45 percent (women) or above 50 percent (men and postmenopausal women) together with raised ferritin, in HFE C282Y homozygotes.
The entry on the register was wrong. It was not replaced but kept, with what holds instead standing next to it.
Where this sits in the engine
This work is on the register, but nothing computes with it today, mostly because the feature it belongs to has not been built yet. It is listed so the numbers on the overview do not claim more than they carry.