Muscle Failure Promotes Greater Muscle Hypertrophy in Low-Load but Not in High-Load Resistance Training

Lasevicius, Schoenfeld, Silva-Batista, Barros, Aihara, Brendon, Longo, Tricoli, Peres, Teixeira · 2022 · Journal of Strength and Conditioning Research 36(2):346–351

What this work gives Aellic

25 untrained men, 8 weeks, unilateral leg extension, volume equated. At 30 % 1RM failure IS required (quadriceps CSA +7.8 % to failure versus +2.8 % not to failure); at 80 % it is not (+8.1 % versus +7.7 %). Strength followed load rather than failure (~33 % at 80 % 1RM versus ~17 % at 30 %).

Correction of 26 July 2026

The added parenthesis “(≥80 % 1RM)” overstated the design: only two loads were tested, 30 % and 80 %. The paper establishes no threshold — where between the two the effect flips is not something it can say. Aellic's 70 % boundary needs a separate justification and has one; it is not this work.

The entry on the register was wrong. It was not replaced but kept, with what holds instead standing next to it.

Where this sits in the engine

1 declared site: constants and thresholds in the code that point at this entry.

Training Muscle growth — sets per muscle 1 site

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